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一名糖尿病患者的慢性炎症性脱髓鞘性多发性神经病:静脉注射免疫球蛋白治疗后病情恶化及对类固醇治疗反应良好

Chronic inflammatory demyelinating polyneuropathy in a diabetic patient: deterioration after intravenous immunoglobulins treatment and favorable response to steroid treatment.

作者信息

Pedersen K, Pandolfo M, Mavroudakis N

机构信息

Department of Neurology, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.

出版信息

Acta Neurol Belg. 2007 Mar;107(1):14-7.

Abstract

The authors report the case of a 54-year old type-2 diabetic female patient with a Chronic Inflammatory Demyelinating Polyneuropathy (CIDP). She progressively developed distal hypoesthesia and tetraparesis. She deteriorated after two courses of intravenous immunoglobulins (IVIG) administration and became rapidly wheelchair bound. After one month of steroid treatment, the patient was walking alone. This case raises the question whether IVIG is to be considered as first line treatment for diabetes associated CIDP.

摘要

作者报告了一例54岁的2型糖尿病女性慢性炎症性脱髓鞘性多发性神经病(CIDP)患者。她逐渐出现远端感觉减退和四肢轻瘫。在接受两个疗程的静脉注射免疫球蛋白(IVIG)治疗后病情恶化,迅速需要依靠轮椅行动。经过一个月的类固醇治疗后,患者能够独立行走。该病例引发了一个问题,即IVIG是否应被视为糖尿病相关性CIDP的一线治疗方法。

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