Peng Tao, Zhang Gu-tian, Chen Ming, Chen Shu-qiu, Sun Ze-yu
Department of Urology, Drum Tower Hospital Affiliated to Nanjing University Medcial College, Nanjing, Jiangsu 210008, China.
Zhonghua Nan Ke Xue. 2007 May;13(5):396-9.
To evaluate erectile function in men with renal failure before and after kidney transplantation and the effects of different methods of renal arterial anastomosis.
Fifty-five married males, aged 22-50 years, who had received kidney transplantation at least one year before and whose serum creatinine was under 200 micromol/L , were selected in the study. The end-to-end revascularization to the internal iliac artery was accomplished in 39 of them, and the end-to-side revascularization to the external iliac artery was conducted in 16. Their erectile function was investigated according to the International Index of Erectile Function-5 (IIEF-5) before kidney transplantation and 3, 6 and 9 months after it. The effects of different methods of renal arterial anastomosis were evaluated and hypophyseal hormones determined in 25 of them.
IIEF-5 was higher in the patients 3, 6 and 9 months after transplantation than before it (P < 0.05) and 6 and 9 months after transplantation than 3 months after it (P < 0.05) , so was it in the patients with less than 12 months hemodialysis than those with over 12 months (P < 0.05) and in the patients with end-to-side revascularization to the external iliac artery than those with end-to-end revascularization to the internal iliac artery (P < 0.05). The differences between the level of hypophyseal hormones and that of sex hormones before transplantation were significant (P < 0.05).
Erectile function and the level of hypophyseal hormones were improved after kidney transplantation, and the patients who received end-to-side revascularization to the external iliac artery experienced better erectile function recovery than those who underwent end-to-end revascularization to the internal iliac artery.
评估肾移植前后肾衰竭男性的勃起功能以及不同肾动脉吻合方法的效果。
选取55名已婚男性,年龄在22至50岁之间,他们至少在一年前接受了肾移植且血清肌酐低于200微摩尔/升,纳入本研究。其中39例行髂内动脉端端血管重建术,16例行髂外动脉端侧血管重建术。在肾移植前以及移植后3、6和9个月,根据国际勃起功能指数-5(IIEF-5)对他们的勃起功能进行调查。对其中25名患者评估不同肾动脉吻合方法的效果并测定垂体激素。
移植后3、6和9个月患者的IIEF-5高于移植前(P<0.05),移植后6和9个月高于移植后3个月(P<0.05);血液透析时间少于12个月的患者高于超过12个月的患者(P<0.05);行髂外动脉端侧血管重建术的患者高于行髂内动脉端端血管重建术的患者(P<0.05)。移植前垂体激素水平与性激素水平之间的差异有统计学意义(P<0.05)。
肾移植后勃起功能和垂体激素水平得到改善,行髂外动脉端侧血管重建术的患者比行髂内动脉端端血管重建术的患者勃起功能恢复更好。