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肾移植吻合术:髂内动脉还是髂外动脉?

Kidney transplant anastomosis: internal or external iliac artery?

作者信息

Matheus Wagner E, Reis Leonardo Oliveira, Ferreira Ubirajara, Mazzali Marilda, Denardi Fernandes, Leitao Victor A, Pedro Renato N, Netto Nelson R

机构信息

Division of Urology, State University of Campinas, Sao Paulo, Brazil.

出版信息

Urol J. 2009 Fall;6(4):260-6.

Abstract

INTRODUCTION

We compared the best technique for arterial anastomosis in kidney transplantation, end-to-side anastomosis to the external iliac artery or end-to-end anastomosis to the internal iliac artery.

MATERIALS AND METHODS

A total of 38 patients with end-stage renal disease who received a kidney transplant from a deceased donor were randomized into two groups in order to undergo either end-to-end anastomosis to the internal iliac artery or end-to-side anastomosis to the external iliac artery. Length of arterial anastomosis, cold ischemia time, hospital stay, serum creatinine level, recovery of urinary output, and surgical and clinical complications during hospitalization were evaluated. After 3 years, in the patients with a functioning allograft, creatinine clearance measure, Doppler ultrasonographic study, survival, graft loss, and erectile function were compared between the two groups.

RESULTS

Postoperative analyses showed similar recovery of urinary output (P = .39) and creatinine (P = .95) between the two groups. No differences in clinical (P = .55) and surgical (P = .80) complications or in hospital stay (P = .90) were noted. The 3-year follow-up demonstrated no differences in Doppler ultrasonography results, creatinine clearance (P = .80), patient survival (P = .22), and graft loss (P = .72). Erectile dysfunction was similar, being related only to pre-operative medical history and age.

CONCLUSION

Both techniques showed similar results in short- and long-term follow-ups. Larger prospective studies are warranted to clarify the risk of renal artery stenosis and development of erectile dysfunction.

摘要

引言

我们比较了肾移植中动脉吻合的最佳技术,即端侧吻合至髂外动脉或端端吻合至髂内动脉。

材料与方法

共有38例接受已故供体肾移植的终末期肾病患者被随机分为两组,分别接受髂内动脉端端吻合或髂外动脉端侧吻合。评估动脉吻合长度、冷缺血时间、住院时间、血清肌酐水平、尿量恢复情况以及住院期间的手术和临床并发症。3年后,对移植肾功能良好的患者,比较两组之间的肌酐清除率测量、多普勒超声检查、生存率、移植肾丢失率和勃起功能。

结果

术后分析显示两组之间尿量恢复情况(P = 0.39)和肌酐水平(P = 0.95)相似。临床并发症(P = 0.55)、手术并发症(P = 0.80)或住院时间(P =  0.90)均无差异。3年随访显示,多普勒超声检查结果、肌酐清除率(P = 0.80)、患者生存率(P = 0.22)和移植肾丢失率(P = 0.72)均无差异。勃起功能障碍情况相似,仅与术前病史和年龄有关。

结论

两种技术在短期和长期随访中均显示出相似的结果。需要进行更大规模的前瞻性研究以阐明肾动脉狭窄的风险和勃起功能障碍的发生情况。

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