Qi Shi-yong, Wang Meng, Xu Yong
Research Laboratory of Prostate Diseases, Tianjin Urology Institute, Tianjin 300211, China.
Zhonghua Nan Ke Xue. 2007 May;13(5):453-6.
As the potent professional antigen present cell, dendritic cells (DC) play an important role in the initiation for anti-tumor immunity. Prostate cancer (PCa) can reduce the number and function of tumor infiltrated dendritic cells (TIDC) by a series of complicated mechanisms, escaping from immunosurveillance. With the development of immunology, more and more studies focus on TIDC and DC-based vaccines for PCa. However, all these studies are still at the exploratory stage. Here is a review of the related literature.
作为强大的专业抗原呈递细胞,树突状细胞(DC)在抗肿瘤免疫的启动中发挥着重要作用。前列腺癌(PCa)可通过一系列复杂机制减少肿瘤浸润树突状细胞(TIDC)的数量和功能,从而逃避免疫监视。随着免疫学的发展,越来越多的研究聚焦于PCa的TIDC和基于DC的疫苗。然而,所有这些研究仍处于探索阶段。以下是相关文献综述。