Roozbehi A, Almasi-Tork S, Piryaee A, Sadeghi Y
Anatomical Sciences Department, University of Medical Sciences, Yasuj, Iran.
Indian J Exp Biol. 2007 May;45(5):469-74.
Cadmium (Cd) is one of the environmental contaminant and because of its non-decomposable character, it can damage nature. In this study, TEM was used in order to assess the ultrastructural effects of Cd on photorececptor and ganglionic cells of mouse retinal layer. Apoptotic nuclei, heterochromatic nuclei, deletion of nucleus membrane, invisible nucleolus, and apoptotic cells with mitochondrial changes were observed in mice embryo (days 15 of gestation) following CdCl2 injection to mothers on day 9 of gestation. Cadmium exposure caused apoptotic changes both in photoreceptors and ganglionic cells.
镉（Cd）是一种环境污染物，因其不可分解的特性，会对自然造成破坏。在本研究中，使用透射电子显微镜（TEM）来评估镉对小鼠视网膜层光感受器和神经节细胞的超微结构影响。在妊娠第9天给母鼠注射氯化镉后，在小鼠胚胎（妊娠第15天）中观察到凋亡细胞核、异染色质核、核膜缺失、核仁不可见以及线粒体发生变化的凋亡细胞。镉暴露导致光感受器和神经节细胞均出现凋亡变化。
