Kammann J, Dornbach G, Vollenberg C, Hille P
Abteilung Augenheilkunde, St.-Johannes-Hospital, Dortmund 1, Bundesrepublik Deutschland.
Fortschr Ophthalmol. 1991;88(5):438-41.
Viscoelastic substances in correlation with intraocular hypotony have gained great significance in low-irritation cataract surgery within the last few years. The differences in their chemical properties, and thus in their effect on the eye, formed the grounds for a controlled clinical study comparing sodium hyaluronic acid, representing the group of glucosamine glykanes, and hydroxypropylmethyl cellulose (HPMC), representing the group of cellulose ethers. Two hundred cataract patients, excluding those suffering from diabetes mellitus, glaucoma and severe corneal damage, were examined on the 1st, 2nd and 5th postoperative day, as well as 4 weeks postoperatively. Statistically, no significant differences were found as regards IOP and postoperative anterior chamber irritation. From the economical point of view, methocel (HPMC) should be preferred to sodium hyaluronic acid in routine cataract surgery due to the lower costs.
在过去几年中,与低眼压相关的粘弹性物质在低刺激性白内障手术中具有重要意义。它们化学性质的差异,进而对眼睛产生的影响,为一项对照临床研究奠定了基础,该研究比较了代表氨基葡萄糖聚糖组的透明质酸钠和代表纤维素醚组的羟丙基甲基纤维素(HPMC)。200例白内障患者,排除患有糖尿病、青光眼和严重角膜损伤的患者,在术后第1天、第2天和第5天以及术后4周进行检查。从统计学角度来看,在眼压和术后前房刺激方面未发现显著差异。从经济角度来看,由于成本较低,在常规白内障手术中,甲基纤维素(HPMC)应优于透明质酸钠。