Hiss P, Fahl G
Universitäts-Augenklinik, Lübeck, Bundesrepublik Deutschland.
Fortschr Ophthalmol. 1991;88(5):562-5.
A pattern electroretinogram (PERG) was recorded in patients in the initial stages of visual field defects resulting from open-angle glaucoma, in patients with ocular hypertension (OHT) and in age-matched controls. In both groups the visual acuity was above 0.8. Counterphasing checkerboard patterns were used as visual stimuli with a check size of 0.8 degrees and a range of reversal rates from 6 to 36 reversals/s. The most significant reductions of amplitudes due to glaucoma and OHT were observed at rates of 18 and 24 reversals/s (glaucoma: P less than 0.005 at 18 and 24 reversals/s, OHT: P less than 0.0005 at 18 reversals/s and P less than 0.0025 at 24 reversals/s). At reversal rates of 6 and 36 reversals/s the PERG was either not reduced (glaucoma and OHT: P greater than 0.01 at 36 reversals/s, OHT: P greater than 0.01 at 6 reversals/s) or reduced only marginally (glaucoma: P less than 0.01 at 6 reversals/s). When one takes the 95% confidence limits of normals into consideration, it is obvious that patients with glaucoma and patients with OHT have pathologic PERGs more often at 18 reversals/s than at other temporal frequencies.
对开角型青光眼所致视野缺损初期的患者、高眼压症（OHT）患者以及年龄匹配的对照组进行图形视网膜电图（PERG）记录。两组患者的视力均高于0.8。使用反相棋盘格图形作为视觉刺激，方格大小为0.8度，反转频率范围为6至36次/秒。青光眼和高眼压症导致的振幅最大降幅出现在18次/秒和24次/秒的频率时（青光眼：18次/秒和24次/秒时P<0.005；高眼压症：18次/秒时P<0.0005，24次/秒时P<0.0025）。在6次/秒和36次/秒的反转频率时，PERG要么未降低（青光眼和高眼压症：36次/秒时P>0.01；高眼压症：6次/秒时P>0.01），要么仅略有降低（青光眼：6次/秒时P<0.01）。当考虑正常范围的95%置信区间时，很明显青光眼患者和高眼压症患者在18次/秒时出现病理性PERG的情况比其他时间频率时更常见。
