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农药制剂的毒性及其商业限制与动物中毒频率的关系。

Relationship of the toxicity of pesticide formulations and their commercial restrictions with the frequency of animal poisonings.

作者信息

Martínez-Haro Mónica, Mateo Rafael, Guitart Raimon, Soler-Rodríguez Francisco, Pérez-López Marcos, María-Mojica Pedro, García-Fernández Antonio J

机构信息

Instituto de Investigación en Recursos Cinegéticos, IREC (CSIC-UCLM-JCCM), Ronda de Toledo s/n, E-13071 Ciudad Real, Spain.

出版信息

Ecotoxicol Environ Saf. 2008 Mar;69(3):396-402. doi: 10.1016/j.ecoenv.2007.05.006. Epub 2007 Jun 13.

DOI:10.1016/j.ecoenv.2007.05.006
PMID:17570525
Abstract

Deliberate poisoning of domestic animals and wildlife with commercial formulations of pesticides has been documented worldwide. We have compiled the analytical results obtained by four Spanish Laboratories of Veterinary Toxicology since 1990. The frequency of poisonings and the intentional use of pesticides were compared between formulations with restricted and unrestricted use, including the toxicity of the commercial formulations as a covariant in the model. The frequency of poisoning was inversely related with the lethal dose of specific formulations, but not with the amounts consumed in agriculture in Spain. The intentional illegal use of some pesticides as poisons was not affected by the commercial restriction of their formulations, but was inversely correlated with their LD(50). The examination of the data permits us to detect three highly toxic compounds (aldicarb, carbofuran, and strychnine), more widely implicated in animal poisonings than other compounds of similar toxicity.

摘要

在全球范围内,都有关于使用商业农药制剂蓄意毒害家畜和野生动物的记录。我们汇总了自1990年以来西班牙四个兽医毒理学实验室获得的分析结果。对限制使用和非限制使用的制剂之间的中毒频率及农药的蓄意使用情况进行了比较,将商业制剂的毒性作为模型中的协变量。中毒频率与特定制剂的致死剂量呈负相关,但与西班牙农业中的使用量无关。一些农药作为毒药的蓄意非法使用不受其制剂商业限制的影响,但与它们的半数致死量呈负相关。对数据的审查使我们能够检测出三种剧毒化合物(涕灭威、克百威和士的宁),与其他毒性相似的化合物相比,它们在家畜中毒事件中涉及得更为广泛。

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