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[植物接触引起的瞳孔散大]

[Mydriasis caused by plant contact].

作者信息

Wilhelm H, Wilhelm B, Schiefer U

机构信息

Abteilung für Pathophysiologie, Universitäts-Augenklinik, Tübingen, Bundesrepublik Deutschland.

出版信息

Fortschr Ophthalmol. 1991;88(5):588-91.

PMID:1757054
Abstract

Uni- or bilateral dilatation of pupils that are not reactive to light and lack miosis in response to 1% pilocarpine may be caused by contact with plants containing alkaloids such as scopolamine and atropine. Other causes of a non-light-reactive dilated pupil, such as Adie's tonic pupil, third nerve palsy and lesion of the mesencephalic pretectal region, must be excluded before testing the iris sphincter reaction to 1% pilocarpine. Among the naturally growing flowers in Germany, deadly nightshade (Atropa belladonna), jimson weed (thornapple, Datura stramonium) and black henbane (Hyoscyamus niger) contain enough alkaloids to cause mydriasis by direct contact. However, in most cases an accidental mydriasis by plants in Germany is caused by Datura arborea taxa, e.g. Datura suaveolens, D. candida, D. aurea and D. sanguinea. They contain up to 0.6% dry weight scopolamine. These plants can grow very large and are often planted in tubs. They have to be cut back each year before the winter. This is typically how the eye is contaminated by parts of the plants, which can cause dilatation of the pupil mimicing a neuroophthalmological disorder.

摘要

单侧或双侧瞳孔散大,对光无反应且对1%毛果芸香碱无缩瞳反应,可能是由于接触了含有东莨菪碱和阿托品等生物碱的植物所致。在检测虹膜括约肌对1%毛果芸香碱的反应之前,必须排除其他导致瞳孔散大且对光无反应的原因,如阿狄瞳孔、动眼神经麻痹和中脑顶盖前区病变。在德国自然生长的花卉中,颠茄、曼陀罗和黑莨菪含有足够的生物碱,可通过直接接触导致瞳孔散大。然而,在大多数情况下,德国植物意外导致的瞳孔散大是由木本曼陀罗类群引起的,如柔紫曼陀罗、白花曼陀罗、黄花曼陀罗和红花曼陀罗。它们含有高达0.6%干重的东莨菪碱。这些植物可以长得非常大,常种植在花盆中。每年冬季前都必须对其进行修剪。眼睛通常就是这样被植物的部分污染,从而导致瞳孔散大,类似神经眼科疾病。

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