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俄罗斯西北部一家儿科医院的医院获得性感染及抗菌药物使用情况现患率调查

A point prevalence survey of hospital-acquired infections and antimicrobial use in a paediatric hospital in north-western Russia.

作者信息

Hajdu A, Samodova O V, Carlsson T R, Voinova L V, Nazarenko S J, Tjurikov A V, Petrova E G, Tulisov A V, Andresen S, Eriksen H M

机构信息

Norwegian Institute of Public Health, Oslo, Norway.

出版信息

J Hosp Infect. 2007 Aug;66(4):378-84. doi: 10.1016/j.jhin.2007.04.018. Epub 2007 Jun 18.

Abstract

We carried out a one-day prevalence survey of hospital-acquired infections (HAIs) and antimicrobial use in February 2006 in a paediatric hospital in Arkhangelsk, north-western Russia. A total 472 patients aged less than 18 years old were included in the study, of which 395 (84%) had been inpatients in the hospital for at least 48 h on the study day. The overall prevalence of HAI amongst the latter group of patients was 17% [67/395; 95% confidence interval (CI): 13.8-21.2] with upper respiratory tract infections being most frequently diagnosed (45%), followed by lower respiratory tract infections (19%) and urinary tract infections (12%). The highest proportion of HAI was found in patients less than one year old and in those with hospital stays of longer than 10 days. Antimicrobial agents were given to 39% of all hospitalized patients (183/472; 95% CI: 34.5-43.2). Cephalosporins accounted for 39% (82/211) of all antimicrobial prescriptions, followed by the penicillins (22%; 46/211). This study established a baseline for surveillance of HAI and antimicrobial use within the hospital, and facilitated the adoption of targeted infection control measures.

摘要

2006年2月,我们在俄罗斯西北部阿尔汉格尔斯克的一家儿科医院开展了一项为期一天的医院获得性感染(HAIs)及抗菌药物使用情况的患病率调查。共有472名年龄小于18岁的患者纳入该研究,其中395名(84%)在研究当日已住院至少48小时。后一组患者中HAI的总体患病率为17%[67/395;95%置信区间(CI):13.8 - 21.2],最常诊断出的是上呼吸道感染(45%),其次是下呼吸道感染(19%)和尿路感染(12%)。HAI比例最高的是年龄小于1岁的患者以及住院时间超过10天的患者。39%的住院患者(183/472;95%CI:34.5 - 43.2)接受了抗菌药物治疗。头孢菌素占所有抗菌药物处方的39%(82/211),其次是青霉素(22%;46/211)。本研究为该医院内HAI及抗菌药物使用情况的监测建立了基线,并推动了针对性感染控制措施的采用。

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