Saito Shunsuke, Nakatani Takeshi, Niwaya Kazuo, Kobayashi Junjiro, Hanatani Akihisa, Tagusari Osamu, Nakajima Hiroyuki, Miyatake Kunio, Yagihara Toshikatsu, Kitamura Soichiro
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan.
J Artif Organs. 2007;10(2):118-21. doi: 10.1007/s10047-007-0373-4. Epub 2007 Jun 20.
We report three consecutive cases of long-term circulatory support using the HeartMate vented electric (VE) left ventricular assist system (LVAS). The HeartMate VE LVAS dramatically improved the functional status and quality of life of these three patients with end-stage heart failure, and all were successfully bridged to transplantation after 659, 995, and 1055 days of support on the device. Only an antiplatelet agent was used for anticoagulation therapy, and no cerebrovascular event occurred. Although the pump stopped in two of these three patients 665 days and 491 days after implantation, both were supported by the backup pneumatic driver thereafter. The drive-line exit site became infected in one patient and thinning of the left ventricular wall due to an unknown cause occurred in one patient.
我们报告了连续三例使用HeartMate vented electric（VE）左心室辅助系统（LVAS）进行长期循环支持的病例。HeartMate VE LVAS显著改善了这三名终末期心力衰竭患者的功能状态和生活质量，并且在该装置支持659天、995天和1055天后，所有患者均成功过渡到移植。抗凝治疗仅使用了一种抗血小板药物，未发生脑血管事件。尽管这三名患者中有两名在植入后665天和491天泵停止工作，但此后均由备用气动驱动器提供支持。一名患者的驱动线出口部位发生感染，一名患者出现原因不明的左心室壁变薄。
