Gélinas Céline, Johnston Céleste
School of Nursing, McGill University, Montreal, Quebec, Canada.
Clin J Pain. 2007 Jul-Aug;23(6):497-505. doi: 10.1097/AJP.0b013e31806a23fb.
Use of a valid behavioral measure for pain is highly recommended for critically ill, uncommunicative adults. The aim of this study was to validate the English version of the Critical-Care Pain Observation Tool (CPOT) and physiologic indicators [mean arterial pressure, heart rate, respiratory rate, and transcutaneous oxygen saturation (SpO(2))] in critically ill ventilated adults.
A total of 30 conscious and 25 unconscious patients in the intensive care unit participated in the study. Patients were assessed by staff nurses and research team members before, during, and 20 minutes after the 2 following procedures: (1) nociceptive procedure: turning, and (2) non-nociceptive procedure: taking noninvasive blood pressure (NIBP). Conscious ventilated patients provided self-report level of pain.
Interrater reliability of the CPOT was supported with high intraclass correlation coefficients (0.80 to 0.93). Discriminant validity was supported with increases of the CPOT and physiologic indicators, and a decrease in SpO(2) during turning, but remaining stable during NIBP. Conscious patients had higher CPOT scores during turning compared with unconscious patients. For criterion validity, the CPOT scores were correlated to the patients' self-reports of pain, whereas physiologic measures were not. Using a CPOT cutoff score of >3 yielded a sensitivity of 66.7% and a specificity of 83.3%.
The CPOT is a reliable and valid tool to assess pain in critically ill adults. Behavioral indicators represent more valid information in pain assessment than physiologic indicators. Further research is needed to explore how specific critically ill populations (eg, head injury) react to a painful procedure.
对于病情危重、无法交流的成年人,强烈建议使用有效的疼痛行为测量方法。本研究的目的是验证危重症通气成年患者使用的《重症监护疼痛观察工具》(CPOT)英文版以及生理指标[平均动脉压、心率、呼吸频率和经皮血氧饱和度(SpO₂)]。
共有30名意识清醒和25名意识不清的重症监护病房患者参与了本研究。在以下两项操作之前、操作期间以及操作后20分钟,由护士和研究团队成员对患者进行评估:(1)伤害性操作:翻身,以及(2)非伤害性操作:测量无创血压(NIBP)。意识清醒的通气患者提供自我报告的疼痛程度。
CPOT的评分者间信度得到组内相关系数较高(0.80至0.93)的支持。判别效度得到支持,即翻身期间CPOT和生理指标增加,SpO₂降低,但测量NIBP期间保持稳定。意识清醒的患者在翻身期间的CPOT评分高于意识不清的患者。对于效标效度,CPOT评分与患者的疼痛自我报告相关,而生理测量指标则不然。使用CPOT临界值>3时,灵敏度为66.7%,特异度为83.3%。
CPOT是评估危重症成年患者疼痛的可靠且有效的工具。行为指标在疼痛评估中比生理指标代表更有效的信息。需要进一步研究以探索特定危重症人群(如头部受伤患者)对疼痛操作的反应。