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右侧结肠旁粘连松解术治疗慢性盆腔疼痛的前瞻性随机试验

Prospective randomized trial of right-sided paracolic adhesiolysis for chronic pelvic pain.

作者信息

Keltz Martin D, Gera Puja Sharma, Olive David L

机构信息

Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, St. Luke's-Roosevelt Hospital Center, Columbia College of Physicians and Surgeons, New York, New York 10019, USA.

出版信息

JSLS. 2006 Oct-Dec;10(4):443-6.

Abstract

BACKGROUND

Prior study has shown that right paracolic adhesions are found in 90% of patients with chronic pelvic pain and less frequently in pain-free patients. We set out to determine whether paracolic adhesiolysis will reduce site-specific pain.

METHODS

This was a prospective, randomized trial of right paracolic adhesiolysis at the time of diagnostic and operative laparoscopy for chronic pelvic pain. Twenty-five patients with a diagnosis of chronic pelvic pain were randomized to either undergo or withhold lysis of right paracolic adhesions at the time of operative laparoscopy.

RESULTS

Right paracolic adhesions were found in 100% of our patients. For all subjects, there was a significant reduction of right and left lower quadrant pain (P<0.001) following the operative laparoscopy. Those who underwent right paracolic adhesiolysis had significantly greater right pelvic pain reduction than those who did not (P=0.014). There was no difference in the reduction of left or mid pelvic pain between the treatment and control groups.

CONCLUSIONS

Right paracolic adhesiolysis reduces short-term site-specific tenderness in patients with chronic pelvic pain. Patients who would benefit from diagnostic or operative laparoscopy are likely to benefit further from paracolic adhesiolysis.

摘要

背景

先前的研究表明,90%的慢性盆腔疼痛患者存在右侧结肠旁粘连,而在无疼痛的患者中则较少见。我们旨在确定结肠旁粘连松解术是否能减轻特定部位的疼痛。

方法

这是一项针对慢性盆腔疼痛患者在诊断性和手术性腹腔镜检查时进行右侧结肠旁粘连松解术的前瞻性随机试验。25例诊断为慢性盆腔疼痛的患者在手术性腹腔镜检查时被随机分为接受或不接受右侧结肠旁粘连松解术两组。

结果

我们所有患者均发现有右侧结肠旁粘连。对于所有受试者,手术性腹腔镜检查后左右下象限疼痛均显著减轻(P<0.001)。接受右侧结肠旁粘连松解术的患者右侧盆腔疼痛减轻程度明显大于未接受者(P=0.014)。治疗组和对照组在左侧或盆腔中部疼痛减轻方面无差异。

结论

右侧结肠旁粘连松解术可减轻慢性盆腔疼痛患者的短期特定部位压痛。从诊断性或手术性腹腔镜检查中获益的患者可能会从结肠旁粘连松解术中进一步获益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d69/3015764/16edb70ed5df/jsls-10-4-443-g01.jpg

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