Sinkó Bálint, Völgyi Gergely, Horváth Péter, Takaćsne Novák Krisztina
Acta Pharm Hung. 2006;76(4):173-80.
In our previous paper identification methods using chemical reactions and TLC are described for the active ingredients of pharmaceutical preparations in Formula Normales (FoNo VII.). Present paper introduces the development and validation of analytical methods suitable for quantitative determination of paracetamol containing dosage forms in FoNo VII. Titrimetric methods, UV spectroscopy and HPLC are used for assay of paracetamol and accompanying components (e.g. codeine, papaverine, caffeine and acetylsalicylic acid) in these preparations.
在我们之前的论文中，描述了使用化学反应和薄层色谱法对《法定制剂》（FoNo VII.）中药物制剂活性成分的鉴定方法。本文介绍了适用于定量测定FoNo VII.中含对乙酰氨基酚剂型的分析方法的开发和验证。采用滴定法、紫外光谱法和高效液相色谱法对这些制剂中的对乙酰氨基酚及伴随成分（如可待因、罂粟碱、咖啡因和乙酰水杨酸）进行含量测定。
