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[中性微丸的重要性及药物技术考量]

[Importance and pharmaceutical technological considerations of neutral pellets].

作者信息

Kállai Nikolett, Antal István

出版信息

Acta Pharm Hung. 2006;76(4):208-12.

Abstract

There is a growing interest toward the application of neutral pellets as starting excipients for pharmaceutical pellet manufacturing. They serve as alternatives to develope and adapt a relatively simple manufacturing technology compared to pellet agglomeration. Their application has benefits considering the low dose of drugs and the requirement for content uniformity. Further use may be advantageous for preparation of orodispersible tablets or modified release preparations.

摘要

人们对将中性丸剂用作药物丸剂制造的起始辅料的应用兴趣日益浓厚。与丸剂团聚相比,它们可作为开发和采用相对简单制造技术的替代品。考虑到药物的低剂量和含量均匀性的要求,它们的应用具有优势。进一步使用可能有利于口腔崩解片或缓释制剂的制备。

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