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产生肽YY的卵巢甲状腺样类癌作为严重便秘的病因,同时伴有对侧上皮性卵巢癌。

Peptide YY producing strumal carcinoid of the ovary as the cause of severe constipation with contralateral epithelial ovarian cancer.

作者信息

Kawano Kouichiro, Ushijima Kimio, Fujimoto Takefumi, Komai Kan, Kamura Toshiharu

机构信息

Department of Obstetrics and Gynecology, Kurume University, School of Medicine, Kurume, Fukuoka, Japan.

出版信息

J Obstet Gynaecol Res. 2007 Jun;33(3):392-6. doi: 10.1111/j.1447-0756.2007.00544.x.

Abstract

Primary ovarian carcinoid tumors are rare. It has been reported that constipation was a presenting symptom in some patients with ovarian carcinoid. A case of strumal carcinoid of the ovary with contralateral clear cell adenocarcinoma of the ovary discovered with a complaint of constipation is described. Constipation was dramatically improved by resectioning the tumor. The tumor cells were positive for peptide YY (PYY) in the carcinoid component, but not in any other components. The present case could provide evidence of the correlation between constipation and PYY that has been reported elsewhere. Interestingly, the constipation caused by PYY also helped in discovering epithelial ovarian cancer.

摘要

原发性卵巢类癌肿瘤很罕见。据报道,便秘是一些卵巢类癌患者的首发症状。本文描述了一例因便秘就诊而发现的卵巢甲状腺肿类癌合并对侧卵巢透明细胞腺癌的病例。切除肿瘤后便秘症状显著改善。类癌成分中的肿瘤细胞肽YY(PYY)呈阳性,而其他成分均为阴性。本病例可为其他地方报道的便秘与PYY之间的相关性提供证据。有趣的是,由PYY引起的便秘也有助于发现上皮性卵巢癌。

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