Guo Xinxin, Wood Michael F G, Vitkin I Alex
Division of Biophysics and Bioimaging, Ontario Cancer Institute, Toronto, Canada.
Appl Opt. 2007 Jul 10;46(20):4491-500. doi: 10.1364/ao.46.004491.
The spatial distribution of optical rotation alpha and surviving linear polarization fraction beta(L) of light scattered from cylindrical turbid chiral (glucose-containing) and achiral samples is studied using a linear Stokes polarimeter. alpha and beta(L) are measured in and off the incident plane as the detection angle changes from the forward to the backward direction. The experimental results exhibit a complex dependence on the detection geometry: alpha is more sensitive to glucose presence off the incident plane, whereas beta(L) exhibits larger effects in-plane, as validated by polarization sensitive Monte Carlo simulations. A rigorous methodology is presented for optimizing the experimental geometry in the polarimetric examinations of complex random systems.