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黑猩猩中与乙型肝炎病毒及非甲非乙型肝炎病毒感染相关的淋巴细胞和中性粒细胞功能障碍。

Lymphocyte and neutrophil dysfunction associated with hepatitis B virus and hepatitis non-A, non-B virus infection in the chimpanzee.

作者信息

Lafrado L J, Javadian M A, Marr J M, Wright K A, Kelliher J C, Dezzutti C S, Cummins L, Olsen R G

机构信息

Ohio State University, Center for Retrovirus Research, Columbus.

出版信息

J Med Primatol. 1991 Aug;20(6):302-7.

PMID:1757973
Abstract

Chimpanzees were examined for the effect of viral hepatitis infections on specific and nonspecific immune response mechanisms. The data suggest that infection with either hepatitis B virus or hepatitis non-A, non-B virus may result in suppression of cellular immune response components. Mitogen-induced lymphocyte proliferation was lower in virus-infected chimpanzees than in naive animals. Neutrophils from virus infected animals exhibited decreased or altered chemiluminescence kinetics.

摘要

研究了黑猩猩感染病毒性肝炎对特异性和非特异性免疫反应机制的影响。数据表明,感染乙型肝炎病毒或非甲非乙型肝炎病毒可能会导致细胞免疫反应成分受到抑制。病毒感染的黑猩猩中,丝裂原诱导的淋巴细胞增殖低于未感染的动物。病毒感染动物的中性粒细胞表现出化学发光动力学降低或改变。

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Lymphocyte and neutrophil dysfunction associated with hepatitis B virus and hepatitis non-A, non-B virus infection in the chimpanzee.黑猩猩中与乙型肝炎病毒及非甲非乙型肝炎病毒感染相关的淋巴细胞和中性粒细胞功能障碍。
J Med Primatol. 1991 Aug;20(6):302-7.
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