Rana S V, Mehta S, Chopra J S, Nain C K, Dhand U K, Mehta J
J Med Primatol. 1984;13(4):205-17.
An experimental model of protein calorie malnutrition (PCM) was created in young rhesus monkeys. Ulnar and tibial nerves from six monkeys with PCM, six rehabilitated and 12 control monkeys were studied for lipid composition and activity of myelin marker enzyme. Total lipids, myelin marker lipids and activity of myelin marker enzyme, 2', 3'-cyclic nucleotide 3' - phosphohydrolase were decreased, while esterified cholesterol and free fatty acids were increased in PCM as compared to controls. There was partial recovery in myelin marker lipids and complete restoration of other lipids on nutritional rehabilitation.
在幼年恒河猴中建立了蛋白质热量营养不良（PCM）的实验模型。对6只患有PCM的猴子、6只康复猴子和12只对照猴子的尺神经和胫神经进行了脂质组成和髓鞘标记酶活性研究。与对照组相比，PCM组的总脂质、髓鞘标记脂质和髓鞘标记酶2',3'-环核苷酸3'-磷酸水解酶的活性降低，而酯化胆固醇和游离脂肪酸增加。营养康复后，髓鞘标记脂质部分恢复，其他脂质完全恢复。
