Pavlović Rajko, Curković Bozidar, Babić-Naglić Durdica, Kehler Tatjana
Specijalna bolnica za medicinsku rehabilitaciju, Gajeva 2, 49217 Krapinske Toplice.
Reumatizam. 2006;53(1):22-4.
Nonsteroidal anti-inflammatory drugs are the first choice in the tretment of rheumatic diseases. Nonsteroidal-antiinflammatory drugs show high efficacy, but they could be responsible for gastrointestinal and cardiovascular adverse events. When the gastrointestinal risk is generally accepted, cardiovascular risk is still without consensus. Did the discussion about potential cardiovascular risk with nonsteroidal anti-inflammatory drugs influenced their prescription in real life? Data on 201 patients with rheumatoid arthritis show that the prescription of nonselective, nonsteroidal anti-inflammatory drugs remain unchanged. More than two third of the patients use nonsteroidal anti-inflammatory drugs despite they have established cardiovascular disease.
非甾体抗炎药是治疗风湿性疾病的首选药物。非甾体抗炎药疗效显著，但可能会导致胃肠道和心血管不良事件。胃肠道风险已得到普遍认可，而心血管风险仍未达成共识。关于非甾体抗炎药潜在心血管风险的讨论是否影响了它们在现实生活中的处方情况？对201例类风湿关节炎患者的数据显示，非选择性非甾体抗炎药的处方量保持不变。尽管超过三分之二的患者已确诊患有心血管疾病，但他们仍在使用非甾体抗炎药。
