Qiu Hongdeng, Jiang Qiong, Wei Zheng, Wang Xusheng, Liu Xia, Jiang Shengxiang
Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.
J Chromatogr A. 2007 Sep 7;1163(1-2):63-9. doi: 10.1016/j.chroma.2007.06.001. Epub 2007 Jun 7.
A new zwitterionic stationary phase based on silica bonded with 1-alkyl-3-(propyl-3-sulfonate) imidazolium was synthesized and characterized in this paper. The materials have been confirmed and evaluated by elemental analysis, thermogravimetric analysis and X-ray photoelectron spectroscopy. Potassium and calcium were separated simultaneously with several common inorganic anions including an iodate, chloride, bromide, nitrate and iodide on the phase. The effects of the concentration, organic solvent and pH of the eluent on the separation of anions were studied. Operated in the anion-exchange mode, this new stationary phase shows considerable promise for the separation of anions. Bases, vitamins and three imidazolium ionic liquids with different alkyl chains are also separated successfully on this column. The stationary phase has multiple retention mechanisms, such as anion-exchange, electrostatic attraction and repulsion interactions, and hydrophobic interaction between the zwitterionic stationary phase and specimens.
本文合成并表征了一种基于硅胶键合1-烷基-3-(丙基-3-磺酸盐)咪唑鎓的新型两性离子固定相。通过元素分析、热重分析和X射线光电子能谱对材料进行了确认和评估。在该固定相上，钾和钙与几种常见的无机阴离子（包括碘酸盐、氯化物、溴化物、硝酸盐和碘化物）同时分离。研究了洗脱液浓度、有机溶剂和pH值对阴离子分离的影响。以阴离子交换模式操作时，这种新型固定相在阴离子分离方面显示出相当大的潜力。碱、维生素和三种具有不同烷基链的咪唑鎓离子液体也在该柱上成功分离。该固定相具有多种保留机制，如阴离子交换、静电吸引和排斥相互作用，以及两性离子固定相与样品之间的疏水相互作用。
