Qiu Shi-jun, Guo Yan-li, Zhang Xue-lin, Hu Ba-sheng, Zhang Yu-zhong, Wen Ge
Diagnositic Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Nan Fang Yi Ke Da Xue Xue Bao. 2007 Jun;27(6):863-5.
To analyze the magnetic resonance imaging (MRI) features of supratentorial primitive neuroectodermal tumors (sPNET) and improve the diagnosis of this disease.
MRI manifestations of 14 cases of PNET were retrospectively analyzed and compared with their pathological features.
The supratentorial lesions involved the occipital lobe in 4, frontal lobe in 3, fronto-occipital lobe in 2, temporo-occipital lobe in 3, lateral ventricle in 1 case and the saddle region in 1. All the lesions were large in volume and most of them presented heterogeneous signals in MRI. Of the 14 cases, 12 showed cystic degeneration and necrosis, 2 had hemorrhage and 6 showed signs of emptied small blood vessels. Twelve cases had heterogeneous enhancement and 2 had moderate enhancement. Pathologically, 10 cases of neuroblastomas were identified, along with 3 ganglioneuroblastomas and 1 atypical rhabdoid tumor.
MRI findings of PNET are rather characteristic to assist in the diagnosis and treatment of the disease, but a final definite diagnosis still relies on pathological examination.
分析幕上原始神经外胚层肿瘤(sPNET)的磁共振成像(MRI)特征,提高对该疾病的诊断水平。
回顾性分析14例PNET的MRI表现,并与病理特征进行对比。
幕上病变累及枕叶4例、额叶3例、额枕叶2例、颞枕叶3例、侧脑室1例、鞍区1例。所有病变体积较大,MRI上大多表现为信号不均匀。14例中,12例出现囊变坏死,2例有出血,6例显示小血管流空信号。12例呈不均匀强化,2例呈中等强化。病理检查确诊神经母细胞瘤10例,节细胞神经母细胞瘤3例,非典型横纹肌样瘤1例。
PNET的MRI表现具有一定特征性,有助于疾病的诊断和治疗,但最终确诊仍依赖病理检查。