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成人原始神经外胚层肿瘤的计算机断层扫描和磁共振成像表现

Computed tomography and magnetic resonance imaging findings in primitive neuroectodermal tumours in adults.

作者信息

Pickuth D, Leutloff U

机构信息

Department of Radiology, German Cancer Research Centre, Heidelberg.

出版信息

Br J Radiol. 1996 Jan;69(817):1-5. doi: 10.1259/0007-1285-69-817-1.

Abstract

Primitive neuroectodermal tumours (PNET) are highly malignant, undifferentiated supratentorial neoplasms arising from germinal matrix cells of the primitive neural tube. PNET occur primarily in young children; they are extremely rare in adults. PNET frequently seed within the central nervous system and may be multicentric at the time of diagnosis. Previous reports of the neuroradiological findings refer solely to PNET in children. We describe the computed tomography (CT) and magnetic resonance imaging (MRI) appearances in five adult patients with pathologically proven PNET. In our series, PNET were mostly seen as rather large, heterogeneous masses with cystic and necrotic areas, intratumoral haemorrhage and focal calcification. The prominent contrast enhancement on both CT and MRI scans reflects the increased vascularity of PNET.

摘要

原始神经外胚层肿瘤(PNET)是起源于原始神经管生发基质细胞的高度恶性、未分化的幕上肿瘤。PNET主要发生于幼儿;在成人中极为罕见。PNET常播散于中枢神经系统内,在诊断时可能为多中心性。先前关于神经放射学表现的报道仅涉及儿童的PNET。我们描述了5例经病理证实为PNET的成年患者的计算机断层扫描(CT)和磁共振成像(MRI)表现。在我们的病例系列中,PNET大多表现为相当大的、不均匀的肿块,伴有囊性和坏死区域、瘤内出血及局灶性钙化。CT和MRI扫描上显著的对比增强反映了PNET血管增多的情况。

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