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真空辅助闭合技术治疗小儿胸骨切开术后纵隔炎

Vacuum-assisted closure in the treatment of poststernotomy mediastinitis in the paediatric patient.

作者信息

Salazard B, Niddam J, Ghez O, Metras D, Magalon G

机构信息

Department of Paediatric Plastic Surgery, Timone Children's Hospital, 264 rue Saint-Pierre, 13385 Marseille Cedex 05, France.

出版信息

J Plast Reconstr Aesthet Surg. 2008;61(3):302-5. doi: 10.1016/j.bjps.2007.05.004. Epub 2007 Jun 27.

DOI:10.1016/j.bjps.2007.05.004
PMID:17586108
Abstract

INTRODUCTION

Delayed sternal closure after paediatric open heart procedure is often necessary. The risk of delayed sternal closure is infection: superficial wound or sternal and mediastinal infection. The incidence of sternal wound infection reported in the literature varies from 0.5 to 10%. The mortality for poststernotomy deep sternal infection continues to be high--from 14 to 47%. Established treatment includes surgical debridement, drainage and irrigation, antibiotics, frequent change of wound dressing and direct or secondary closure with omentum or pectoral muscle flap.

PATIENTS AND METHODS

Between October 2003 and August 2005, three children, aged from 9 days to 2 years and who had developed severe mediastinitis after cardiac surgery were treated with the vacuum-assisted closure (VAC) system.

RESULTS

The duration of VAC treatment ranged from 12 to 21 days. The response to VAC was rapid with local purulence and C-reactive protein (CRP) both decreasing within 72 h in all cases. After good granulation was obtained, two patients required a thin skin graft.

DISCUSSION

All three children had peritoneal dialysis which did not permit omental use. The use of pectoralis major is a difficult technique in neonates and the haemodynamic conditions were poor in our cases. The VAC technique is a good indication in post-cardiotomy mediastinitis in children: it plays a role in the reduction of infection and provides good healing.

摘要

引言

小儿心脏直视手术后延迟关闭胸骨常常是必要的。延迟关闭胸骨的风险是感染,包括表浅伤口感染或胸骨及纵隔感染。文献报道的胸骨伤口感染发生率在0.5%至10%之间。胸骨切开术后深部胸骨感染的死亡率仍然很高,在14%至47%之间。既定的治疗方法包括手术清创、引流和冲洗、使用抗生素、频繁更换伤口敷料以及用网膜或胸肌瓣直接或二期关闭伤口。

患者与方法

2003年10月至2005年8月期间,对3名年龄在9天至2岁之间、心脏手术后发生严重纵隔炎的儿童采用负压封闭引流(VAC)系统进行治疗。

结果

VAC治疗持续时间为12至21天。所有病例对VAC的反应迅速,局部脓性分泌物和C反应蛋白(CRP)在72小时内均下降。在获得良好的肉芽组织后,两名患者需要进行薄皮移植。

讨论

所有3名儿童均进行了腹膜透析,无法使用网膜。在新生儿中使用胸大肌是一项困难的技术,而且我们病例中的血流动力学状况较差。VAC技术是小儿心脏术后纵隔炎的良好适应证:它在减少感染方面发挥作用,并能实现良好的愈合。

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