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本文引用的文献

1
Risk factors for surgical site infection after cardiac surgery in children.儿童心脏手术后手术部位感染的危险因素。
Ann Thorac Surg. 2010 Jun;89(6):1833-41; discussion 1841-2. doi: 10.1016/j.athoracsur.2009.08.081.
2
Combination of continuous irrigation and vacuum-assisted closure is effective for mediastinitis after cardiac surgery in small children.持续冲洗与负压封闭引流联合应用对小儿心脏术后纵隔炎有效。
Interact Cardiovasc Thorac Surg. 2010 Sep;11(3):247-51. doi: 10.1510/icvts.2010.235903. Epub 2010 May 4.
3
Mediastinitis after coronary artery bypass grafting risk factors and long-term survival.冠状动脉旁路移植术后纵隔炎的危险因素和长期生存。
Ann Thorac Surg. 2010 May;89(5):1502-9. doi: 10.1016/j.athoracsur.2010.02.038.
4
Surgicel packing and an erroneous diagnosis of mediastinitis in a neonate.新生儿使用外科止血纱布填塞及纵隔炎的误诊
Tex Heart Inst J. 2010;37(1):116-8.
5
After omental flap transposition, respiratory function and exercise capacity decrease.网膜瓣移位术后,呼吸功能和运动能力下降。
Ann Thorac Cardiovasc Surg. 2010 Aug;16(1):9-15.
6
Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis.氯己定-酒精与聚维酮碘用于手术部位消毒。
N Engl J Med. 2010 Jan 7;362(1):18-26. doi: 10.1056/NEJMoa0810988.
7
Preventing surgical-site infections in nasal carriers of Staphylococcus aureus.预防金黄色葡萄球菌鼻腔携带者的手术部位感染。
N Engl J Med. 2010 Jan 7;362(1):9-17. doi: 10.1056/NEJMoa0808939.
8
Right ventricular rupture due to recurrent mediastinal infection with a closed chest.因复发性纵隔感染伴闭合性胸腔导致的右心室破裂
Interact Cardiovasc Thorac Surg. 2010 Mar;10(3):470-2. doi: 10.1510/icvts.2009.223891. Epub 2009 Dec 3.
9
Cardiopulmonary effects of continuous negative pressure wound therapy in swine.持续负压伤口治疗对猪心肺功能的影响
Ann Thorac Surg. 2009 Oct;88(4):1277-83. doi: 10.1016/j.athoracsur.2009.06.027.
10
The impact of vacuum-assisted venous drainage and miniaturized bypass circuits on blood transfusion in pediatric cardiac surgery.真空辅助静脉引流和小型化体外循环回路对小儿心脏手术输血的影响。
ASAIO J. 2009 Jan-Feb;55(1):117-20. doi: 10.1097/MAT.0b013e31819142f1.

小儿心脏手术中的纵隔炎:预防、诊断与治疗

Mediastinitis in pediatric cardiac surgery: Prevention, diagnosis and treatment.

作者信息

Durandy Yves

机构信息

Yves Durandy, Perfusion and Intensive Care Unit in Pediatric Cardiac Surgery, Institut Hospitalier Jacques Cartier, Avenue du Noyer Lambert, 91300 Massy, France.

出版信息

World J Cardiol. 2010 Nov 26;2(11):391-8. doi: 10.4330/wjc.v2.i11.391.

DOI:10.4330/wjc.v2.i11.391
PMID:21179306
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3006475/
Abstract

In spite of advances in the management of mediastinitis following sternotomy, mediastinitis is still associated with significant morbidity. The prognosis is much better in pediatric surgery compared to adult surgery, but the prolonged hospital stays with intravenous therapy and frequent required dressing changes that occur with several therapeutic approaches are poorly tolerated. Prevention includes nasal decontamination, skin preparation, antibioprophylaxis and air filtration in the operating theater. The expertise of the surgical team is an additional factor that is difficult to assess precisely. Diagnosis is often very simple, being made on the basis of a septic state with wound modification, while retrosternal puncture and CT scan are rarely useful. Treatment of mediastinitis following sternotomy is always a combination of surgical debridement and antibiotic therapy. Continued use of numerous surgical techniques demonstrates that there is no consensus and the best treatment has yet to be determined. However, we suggest that a primary sternal closure is the best surgical option for pediatric patients. We propose a simple technique with high-vacuum Redon's catheter drainage that allows early mobilization and short term antibiotherapy, which thus decreases physiological and psychological trauma for patients and families. We have demonstrated the efficiency of this technique, which is also cost-effective by decreasing intensive care and hospital stay durations, in a large group of patients.

摘要

尽管在胸骨切开术后纵隔炎的管理方面取得了进展,但纵隔炎仍然与显著的发病率相关。与成人手术相比,小儿手术的预后要好得多,但几种治疗方法所带来的静脉治疗导致的住院时间延长以及频繁更换敷料,患儿耐受性较差。预防措施包括鼻腔去污、皮肤准备、抗生素预防以及手术室的空气过滤。手术团队的专业水平是另一个难以精确评估的因素。诊断通常非常简单,基于伴有伤口改变的感染状态即可做出诊断,而胸骨后穿刺和CT扫描很少有用。胸骨切开术后纵隔炎的治疗始终是手术清创和抗生素治疗的结合。众多手术技术的持续应用表明,目前尚无共识,最佳治疗方法尚未确定。然而,我们认为一期胸骨闭合术是小儿患者的最佳手术选择。我们提出一种采用高负压雷东导管引流的简单技术,该技术可实现早期活动和短期抗生素治疗,从而减少患者及其家庭的生理和心理创伤。我们已经在大量患者中证明了该技术的有效性,通过缩短重症监护时间和住院时间,该技术还具有成本效益。