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小儿心脏手术中的纵隔炎:预防、诊断与治疗

Mediastinitis in pediatric cardiac surgery: Prevention, diagnosis and treatment.

作者信息

Durandy Yves

机构信息

Yves Durandy, Perfusion and Intensive Care Unit in Pediatric Cardiac Surgery, Institut Hospitalier Jacques Cartier, Avenue du Noyer Lambert, 91300 Massy, France.

出版信息

World J Cardiol. 2010 Nov 26;2(11):391-8. doi: 10.4330/wjc.v2.i11.391.

Abstract

In spite of advances in the management of mediastinitis following sternotomy, mediastinitis is still associated with significant morbidity. The prognosis is much better in pediatric surgery compared to adult surgery, but the prolonged hospital stays with intravenous therapy and frequent required dressing changes that occur with several therapeutic approaches are poorly tolerated. Prevention includes nasal decontamination, skin preparation, antibioprophylaxis and air filtration in the operating theater. The expertise of the surgical team is an additional factor that is difficult to assess precisely. Diagnosis is often very simple, being made on the basis of a septic state with wound modification, while retrosternal puncture and CT scan are rarely useful. Treatment of mediastinitis following sternotomy is always a combination of surgical debridement and antibiotic therapy. Continued use of numerous surgical techniques demonstrates that there is no consensus and the best treatment has yet to be determined. However, we suggest that a primary sternal closure is the best surgical option for pediatric patients. We propose a simple technique with high-vacuum Redon's catheter drainage that allows early mobilization and short term antibiotherapy, which thus decreases physiological and psychological trauma for patients and families. We have demonstrated the efficiency of this technique, which is also cost-effective by decreasing intensive care and hospital stay durations, in a large group of patients.

摘要

尽管在胸骨切开术后纵隔炎的管理方面取得了进展,但纵隔炎仍然与显著的发病率相关。与成人手术相比,小儿手术的预后要好得多,但几种治疗方法所带来的静脉治疗导致的住院时间延长以及频繁更换敷料,患儿耐受性较差。预防措施包括鼻腔去污、皮肤准备、抗生素预防以及手术室的空气过滤。手术团队的专业水平是另一个难以精确评估的因素。诊断通常非常简单,基于伴有伤口改变的感染状态即可做出诊断,而胸骨后穿刺和CT扫描很少有用。胸骨切开术后纵隔炎的治疗始终是手术清创和抗生素治疗的结合。众多手术技术的持续应用表明,目前尚无共识,最佳治疗方法尚未确定。然而,我们认为一期胸骨闭合术是小儿患者的最佳手术选择。我们提出一种采用高负压雷东导管引流的简单技术,该技术可实现早期活动和短期抗生素治疗,从而减少患者及其家庭的生理和心理创伤。我们已经在大量患者中证明了该技术的有效性,通过缩短重症监护时间和住院时间,该技术还具有成本效益。

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