Isbister W H
Department of Surgery, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Ann Saudi Med. 1992 Sep;12(5):429-33. doi: 10.5144/0256-4947.1992.429.
Malignant neoplasms of the colon, rectum, and anus are relatively uncommon in the Kingdom of Saudi Arabia. This paper documents the King Faisal Specialist Hospital and Research Centre tumor registry colorectal cancer data base. Between June 1975 and December 1989, 622 patients were registered with malignant colorectal and anal tumors. There were 383 males and 239 females. The average ages were 53.5 years and 47.8 years. The majority of patients were Saudi. The single most common site for large bowel malignancy was the rectum. There were 455 simple adenocarcinomata, 39 mucinoud adenocarcinomata, and 17 signet-ring adenocarcinomata. There were 46 epidermoid cancers. Most of the tumors were moderately differentiated and the majority of tumors were greater than 5 cm in diameter. Fifty-seven patients had disease localized to the organ of origin. 56 patients had disease which was localized but directly invading an adjacent organ, and the remaining patients had nodal or distant spread. The greatest majority of patients came from either Makkah or Riyadh. There were no provincial differences in the disease. There were more smaller and differentiated lesions in the sigmoid colon than in the rectum and right colon, but more patients with metastatic disease to the nodes or distant organs. Tumors were smaller at presentation and less disseminated in Saudis than in the other Arabs.
在沙特阿拉伯王国，结肠、直肠和肛门的恶性肿瘤相对不常见。本文记录了法赫德国王专科医院和研究中心肿瘤登记处的结直肠癌数据库。1975年6月至1989年12月期间，有622例患有结肠、直肠和肛门恶性肿瘤的患者进行了登记。其中男性383例，女性239例。平均年龄分别为53.5岁和47.8岁。大多数患者是沙特人。大肠恶性肿瘤最常见的单一部位是直肠。有455例单纯腺癌、39例黏液腺癌和17例印戒腺癌。有46例表皮样癌。大多数肿瘤为中度分化，大多数肿瘤直径大于5厘米。57例患者的疾病局限于原发器官。56例患者的疾病局限但直接侵犯相邻器官，其余患者有淋巴结或远处转移。绝大多数患者来自麦加或利雅得。该疾病在各省之间没有差异。乙状结肠中较小且分化的病变比直肠和右结肠更多，但有更多患者出现淋巴结或远处器官转移。沙特患者的肿瘤在初诊时较小且扩散程度低于其他阿拉伯人。
