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Long-term stability of diazepam injections.

作者信息

Fyllingen G, Kristiansen F, Roksvaag P O

机构信息

Military Pharmaceutical Laboratory Joint Medical Service, Oslo, Norway.

出版信息

Pharm Acta Helv. 1991;66(2):44-6.

PMID:1758892
Abstract

Diazepam and its main degradation product 2-methyl-amino-5-chlorobenzophenon (MACB) were quantitatively determined by HPLC and spectrophotometry in one- to ten-years-old diazepam injections. The content of diazepam was within the specifications in all the samples. Not more than 1.5% degradation of diazepam was found after ten years.

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