Fyllingen G, Kristiansen F, Roksvaag P O
Military Pharmaceutical Laboratory Joint Medical Service, Oslo, Norway.
Pharm Acta Helv. 1991;66(2):44-6.
Diazepam and its main degradation product 2-methyl-amino-5-chlorobenzophenon (MACB) were quantitatively determined by HPLC and spectrophotometry in one- to ten-years-old diazepam injections. The content of diazepam was within the specifications in all the samples. Not more than 1.5% degradation of diazepam was found after ten years.