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[猫白血病病毒和肉瘤病毒]

[Feline leukemogenic and sarcomatogenic viruses].

作者信息

Parodi A L

出版信息

C R Seances Soc Biol Fil. 1975;169(3 Suppl):794-806.

PMID:175893
Abstract

Feline Leukemia and sarcoma viruses (FeLV, FeSV) are RNA viruses, belonging to the Oncornavirus group. They possess common morphological, biochemical and immunological properties, with viruses of leukemia and sarcoma already known in others mammalian and avian species. FeLV is widely present in feline population and its transmission is by horizontal way. FeLV and FeSV are oncogenic for others species, i.e., dog and some non-human primates but as far as we know, the human receptivity is not established. A correlation between humoral antibody directed against membran new-antigens and regression of tumors induced by FeSV, led to actual investigations on vaccination.

摘要

猫白血病病毒和肉瘤病毒(FeLV、FeSV)是RNA病毒,属于肿瘤病毒组。它们具有共同的形态学、生物化学和免疫学特性,在其他哺乳动物和鸟类中已发现白血病和肉瘤病毒。FeLV广泛存在于猫群中,其传播途径为水平传播。FeLV和FeSV对其他物种具有致癌性,即狗和一些非人类灵长类动物,但据我们所知,尚未确定人类的易感性。针对膜新抗原的体液抗体与FeSV诱导的肿瘤消退之间的相关性,引发了目前关于疫苗接种的研究。

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