Gandapur Abdus Salam Khan, Manan Modoodul, Nazir Ghazala, Uzma Naeen, Chawla Javaid Akhtar, Jadoon Azhar, Tauqeer Asya
Pathology Department, Women Medical College, Abbottabad, Pakistan.
J Ayub Med Coll Abbottabad. 2006 Oct-Dec;18(4):16-20.
One of the important effects of exercise on human body is on the metabolic system especially on lipids; elevated lipids and lipoprotein are risk factors for coronary heart disease. This case-control study was conducted to compare the lipid profile and apo-protein B levels in sedentary workers and subjects involved in regular exercise.
The study was conducted at Women Medical College Abbottabad, from July 2004 to January 2005. Subjects were civilians and army men involved in regular exercise for more than 6 months duration (test group) and sedentary workers (control group). The age, body weight, height, waist hip ratio and other related findings were recorded on a special proforma. Fasting blood samples were taken and were analyzed for lipid profile and apoprotein B levels. Statistical analysis was done by the Chi square and the Student t tests and level of significance was recorded.
The subjects comprised 29 army men, 24 civilians and 39 sedentary workers. Significant differences were found between the control and test groups for WHR, total cholesterol, HDL, LDL, Triglycerides, Apo B, and Cholesterol/HDL ratio; in addition the civilian group also showed significant differences from the control group in BMI values. Although LDL levels were lower in army than sedentary group, the difference was statistically nonsignificant. Significant differences were found between the army and civilian groups in age, HDL, Triglycerides and Apo B values.
Long term aerobic exercise has beneficial effects in decreasing Apo- protein B levels, LDL levels and total cholesterol /HDL ratio. Exercise habits should be encouraged in general population to decrease the cardiovascular disease risk.
运动对人体的重要影响之一在于代谢系统，尤其是对脂质的影响；脂质和脂蛋白升高是冠心病的危险因素。本病例对照研究旨在比较久坐不动的工作者与经常运动的受试者的血脂谱和载脂蛋白B水平。
该研究于2004年7月至2005年1月在阿伯塔巴德女子医学院进行。受试者包括定期锻炼超过6个月的平民和军人（试验组）以及久坐不动的工作者（对照组）。使用特制表格记录年龄、体重、身高、腰臀比及其他相关数据。采集空腹血样并分析血脂谱和载脂蛋白B水平。采用卡方检验和学生t检验进行统计分析并记录显著性水平。
受试者包括29名军人、24名平民和39名久坐不动的工作者。对照组和试验组在腰臀比、总胆固醇、高密度脂蛋白、低密度脂蛋白、甘油三酯、载脂蛋白B以及胆固醇/高密度脂蛋白比值方面存在显著差异；此外，平民组与对照组在体重指数值方面也存在显著差异。尽管军人组的低密度脂蛋白水平低于久坐组，但差异无统计学意义。军人组和平民组在年龄、高密度脂蛋白、甘油三酯和载脂蛋白B值方面存在显著差异。
长期有氧运动对降低载脂蛋白B水平、低密度脂蛋白水平以及总胆固醇/高密度脂蛋白比值具有有益作用。应鼓励普通人群养成运动习惯以降低心血管疾病风险。
