Viani Flávio Cesar, Cazares Viani Paula Regina, Gutierrez Rivera Irma Nelly, Gonçalves da Silva Eriques, Rodrigues Paula Claudete, Gambale Walderez
Laboratorio de Micologia, Departamento de Microbiologia, ICB-USP, Av Prof Lineu Prestes 1374, CEP 05508-900, São Paulo, SP, Brazil.
Rev Iberoam Micol. 2007 Mar;24(1):19-23. doi: 10.1016/s1130-1406(07)70004-9.
Microsporum canis is the main zoophylic dermatophyte in dogs and cats, and it is also an important zoonotic agent. The literature showed that cats are asymptomatic carriers of M. canis. This is apparently due to host resistance and/or the presence of strains with lower virulence. This study was aimed to evaluate the keratinolytic, elastinolytic and collagenolytic activities of M. canis strains and their relationship with symptomatic and asymptomatic cats. In addition, these strains were analysed by RFLP. The strains isolated from cats with clinical dermatophytosis had higher keratinase and elastase activity than those isolated from asymptomatic animals (p minus than 0.05). There were not differences in RFLP patterns based on Hind III digestion.
犬小孢子菌是犬猫主要的亲动物性皮肤癣菌，也是一种重要的人畜共患病原体。文献表明，猫是犬小孢子菌的无症状携带者。这显然是由于宿主抵抗力和/或低毒力菌株的存在。本研究旨在评估犬小孢子菌菌株的角蛋白分解、弹性蛋白分解和胶原蛋白分解活性及其与有症状和无症状猫的关系。此外，通过限制性片段长度多态性（RFLP）分析这些菌株。从临床皮肤癣菌病猫分离的菌株比从无症状动物分离的菌株具有更高的角蛋白酶和弹性蛋白酶活性（p小于0.05）。基于Hind III消化的RFLP模式没有差异。
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