Rabin H, Adamson R H, Neubauer R H, Cicmanec J L, Wallen W C
Cancer Res. 1976 Feb;36(2 pt 2):715-9.
The nature of Herpesvirus saimiri-induced disease in owl monkeys is described with emphasis on those biological parameters useful in monitoring the disease. These parameters are lymphocyte response to general mitogens, lymphocyte-infective centers, and antibody to virus-associated early antigen. Human interferon was used in treating owl monkeys with virus-induced leukemia. In 2 animals evidence was obtained that suggested a positive antileukemic effect.
描述了赛氏疱疹病毒在猫头鹰猴中引起的疾病的性质,重点关注那些有助于监测该疾病的生物学参数。这些参数包括淋巴细胞对一般促有丝分裂原的反应、淋巴细胞感染中心以及病毒相关早期抗原的抗体。使用人干扰素治疗患有病毒诱导白血病的猫头鹰猴。在2只动物中获得的证据表明存在积极的抗白血病作用。