Requena Maria A, Palma Daniel A, Popescu Bodgan M
Hospital Escuela José Francisco de San Martin de la Facultad de Medicina de la UNNE, Corrientes.
Medicina (B Aires). 2007;67(2):156-8.
Relapsing polychondritis is a multysistemic inflammatory disease, of unknown etiology. It is characterized by recurrent episodes of inflammation with progressive destruction of cartilaginous structures and connective tissue. It may also affect tissues that contain proteoglycans like eyes, heart, kidney, and blood vessels causing a picture of vasculitis. We report here the case of a patient with relapsing polychondritis and seizures. The magnetic resonance imaging of the brain showed multiple hyperintense signals in the T2 weighted images and fluid-attenuated inversion recovery (FLAIR), suggesting ischemic injuries, that improved with high doses of glucocorticoids. We remark the unusual presentation with neurological involvement in this uncommon disease that has improved with treatment.
复发性多软骨炎是一种病因不明的多系统炎症性疾病。其特征为炎症反复发作,伴有软骨结构和结缔组织的进行性破坏。它还可能影响含有蛋白聚糖的组织,如眼睛、心脏、肾脏和血管,导致血管炎表现。我们在此报告一例患有复发性多软骨炎并伴有癫痫发作的患者。脑部磁共振成像在T2加权像和液体衰减反转恢复序列(FLAIR)上显示多个高信号,提示缺血性损伤,高剂量糖皮质激素治疗后有所改善。我们注意到这种罕见疾病伴有神经受累的不寻常表现,经治疗后有所改善。