Michels H, Greiner K, Heinz C, Horneff G, Ganser G
Deutsches Zentrum für Kinder- und Jugendrheumatologie, Garmisch-Partenkirchen.
Klin Monbl Augenheilkd. 2007 Jun;224(6):473-6. doi: 10.1055/s-2007-963091.
In childhood and adolescence, uveitis is part of the clinical spectrum of many inflammatory-rheumatic diseases. Besides juvenile idiopathic arthritis juvenile, ankylosing spondylitis, infection-associated arthritides, infantile sarcoidosis, systemic vasculitides, inflammatory bowel diseases, hereditary autoinflammatory syndromes and the TINU syndrome have to be excluded. These inflammatory diseases can be differentiated clinically in connection with immunogenetic and molecular genetic investigations. Early diagnosis of uveitis as well as the underlying diseases is mandatory for an early treatment and therefore for a good prognosis.
在儿童期和青少年期,葡萄膜炎是许多炎症性风湿性疾病临床谱的一部分。除了青少年特发性关节炎、幼年型强直性脊柱炎、感染相关性关节炎外,还必须排除婴儿结节病、系统性血管炎、炎症性肠病、遗传性自身炎症综合征和TINU综合征。这些炎症性疾病可结合免疫遗传学和分子遗传学研究进行临床鉴别。葡萄膜炎及其潜在疾病的早期诊断对于早期治疗以及良好预后至关重要。