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[青少年特发性关节炎与葡萄膜炎:筛查与抗炎治疗]

[Juvenile idiopathic arthritis and uveitis: screening and anti-inflammatory therapy].

作者信息

Heiligenhaus Arnd, Mingels Anne, Neudorf Ulrich, Ganser Gerd

机构信息

Augenabteilung am St.-Franziskus-Hospital, Muenster.

出版信息

Klin Monbl Augenheilkd. 2003 Nov;220(11):738-53. doi: 10.1055/s-2003-44613.

Abstract

This article provides an overview of the rheumatic diseases in childhood, their pathogenesis, epidemiology, diagnosis and clinical course. EULAR, ACR and the current ILAR-classification are compared. The antiinflammatory medical treatment is described. The characteristics of uveitis in the various forms of arthritis are reviewed. The prognostic factors for uveitis manifestation, the clinical course, complications, the prognostic factors for visual loss, and the diverse antiinflammatory medical regimens are evaluated. The suggestions of the "uveitis in childhood study group" concerning screening and treatment of uveitis in patients with juvenile idiopathic arthritis are provided, and a nation-wide documentation of these patients is described.

摘要

本文概述了儿童风湿性疾病、其发病机制、流行病学、诊断及临床病程。比较了欧洲抗风湿病联盟(EULAR)、美国风湿病学会(ACR)及当前国际风湿病学联盟(ILAR)的分类。描述了抗炎药物治疗。回顾了各种关节炎形式中葡萄膜炎的特征。评估了葡萄膜炎表现的预后因素、临床病程、并发症、视力丧失的预后因素以及不同的抗炎药物治疗方案。提供了“儿童葡萄膜炎研究组”关于幼年特发性关节炎患者葡萄膜炎筛查和治疗的建议,并描述了对这些患者的全国性记录。

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