Rusakova E V, Bezuglova M S, Frank K D, Alekseenkova L I, Filatov N N
Zh Mikrobiol Epidemiol Immunobiol. 1991 Sep(9):37-40.
The use of the method of cluster selection in mass serological examination makes it possible to obtain statistically significant results with very low expenditures. The coincidence of the results on the number of seronegative children, obtained by the method of cluster selection, with the results of mass serological examination of all children aged 6-7 years in the district (children found to be seronegative to measles constituted 5.5% and 5.0% respectively) is indicative of the statistical significance of the method used in this investigation. The results obtained by the method of cluster selection indicate that the level of protection among the children of the district was high both with respect to measles (94.5 +/- 1.8%) and tetanus (96.5 +/- 1.7%); with respect to diphtheria, the immune stratum was found to be less (91.1 +/- 2.3%). These data may be helpful in working out scientifically substantiated administrative decisions contributing to an increase in the effectiveness of planned mass immunization.
在大规模血清学检查中采用整群抽样方法，能够以极低的成本获得具有统计学意义的结果。通过整群抽样方法得出的血清学阴性儿童数量结果，与该地区所有6至7岁儿童大规模血清学检查的结果相符（麻疹血清学阴性儿童分别占5.5%和5.0%），这表明本研究中使用的方法具有统计学意义。整群抽样方法获得的结果表明，该地区儿童对麻疹（94.5±1.8%）和破伤风（96.5±1.7%）的保护水平较高；对白喉而言，免疫阶层较低（91.1±2.3%）。这些数据可能有助于制定科学合理的行政决策，以提高计划免疫的效果。
