Rusakova E V, Kashliaeva T K, Gusarova L D, Muradova G D
Zh Mikrobiol Epidemiol Immunobiol. 1987 Mar(3):29-33.
The epidemiological and immunological evaluation of two immunization schedules approved by the Orders of the USSR Ministry of Health No. 322 of April 24, 1973, and No. 50 of January 14, 1980, has been made on the basis of the results obtained in the Brest region of the Byelorussian SSR and in the Turkmen SSR. According to these results, the use of the schedule approved by Order No. 50 has made it possible to increase the groups of children receiving correct and timely immunization with measles vaccine by 8.3% and 28.8% and with adsorbed DPT vaccine by 17.2% and 5.5% in the Brest region of the Byelorussian SSR and in the Turkmen SSR respectively. Considerable groups of children have been found to be immunized with deviations from the approved schedules with respect to the scheme and time of immunization: 62.1% and 44.5% in the Brest region, 81.3% and 80.5% in the Turkmen SSR (during the periods of the implementation of Orders No. 322 and No. 50 respectively). Acute respiratory viral infections, bronchitis and pneumonia have proved to be the main reasons for medical exemption from immunization in both republics, these diseases constituting 61.6-71.1% of all medical contraindications. The negative influence of earlier infectious diseases on the level of postvaccinal immunity has been shown.
根据白俄罗斯苏维埃社会主义共和国布列斯特地区和土库曼苏维埃社会主义共和国所取得的成果，对苏联卫生部1973年4月24日第322号命令和1980年1月14日第50号命令批准的两种免疫接种程序进行了流行病学和免疫学评估。根据这些成果，在白俄罗斯苏维埃社会主义共和国布列斯特地区和土库曼苏维埃社会主义共和国，采用第50号命令批准的程序，分别使接受正确及时麻疹疫苗免疫接种的儿童群体增加了8.3%和28.8%，接受吸附百白破疫苗免疫接种的儿童群体增加了17.2%和5.5%。已发现相当多儿童的免疫接种在免疫程序和时间方面偏离了批准的程序：在布列斯特地区分别为62.1%和44.5%，在土库曼苏维埃社会主义共和国分别为81.3%和80.5%（分别在执行第322号和第50号命令期间）。事实证明，急性呼吸道病毒感染、支气管炎和肺炎是这两个共和国医学上免予免疫接种的主要原因，这些疾病占所有医学禁忌的61.6 - 71.1%。已表明既往传染病对疫苗接种后免疫力水平有负面影响。
