Virsaladze D K, Tetradze L O, Dzhavashvili L V, Esaliia N G, Tananashvili D E
Georgian Med News. 2007 May(146):35-7.
The aim of our investigation was to study the peculiarities of serum uric acid (UA) levels in patients with metabolic syndrome (MS) and without it, also correlations between UA and parameters of MS features. 41 patients (mean age - 37,8+/-13,7 years) have been investigated. MS was defined by definitions of WHO (2002), ATPIII and Society of Georgia Endocrinologists (SGE). Exclusion criterion served the gout. Levels of all parameters of MS features and serum UA have been determined. MS was diagnosed in 48,7% of cases. Study group consisted of these patients, and control group - patients without MS. Serum UA levels were significantly higher in the study group in comparison with the control (6,6+/-1,4 vs. 5,4+/-1,3 mg/dl, p=0,007; respectively). In main group the cases of hyperuricemia have been documented significantly frequently than in control (65,0% vs. 33,3%, p=0,043; respectively). Obtained results shown that UA levels significantly higher and hyperuricemia cases significantly frequent at MS, which have to be taking into account during symptomatic treatment of patients.
我们研究的目的是探讨代谢综合征（MS）患者和非代谢综合征患者血清尿酸（UA）水平的特点，以及UA与MS特征参数之间的相关性。我们对41例患者（平均年龄37.8±13.7岁）进行了研究。MS根据世界卫生组织（2002年）、美国国家胆固醇教育计划成人治疗组第三次报告（ATPIII）以及格鲁吉亚内分泌学家协会（SGE）的定义来确定。排除标准为痛风。我们测定了所有MS特征参数和血清UA的水平。48.7%的病例被诊断为MS。研究组由这些患者组成，对照组为无MS的患者。与对照组相比，研究组的血清UA水平显著更高（分别为6.6±1.4 vs. 5.4±1.3mg/dl，p = 0.007）。在主要组中，高尿酸血症的病例记录明显比对照组频繁（分别为65.0% vs. 33.3%，p = 0.043）。获得的结果表明，在MS患者中UA水平显著更高，高尿酸血症病例明显更频繁，这在对患者进行对症治疗时必须予以考虑。
