Satoh Toshifumi, Kakuchi Toyoji
Division of Biotechnology and Macromolecular Chemistry, Graduate School of Engineering, Hokkaido University, Sapporo 060-8628, Japan.
Macromol Biosci. 2007 Aug 7;7(8):999-1009. doi: 10.1002/mabi.200700057.
The synthesis of novel hyperbranched carbohydrate polymers, prepared by the ring-opening multibranching polymerizations of anhydro and dianhydro sugars, is described. The hyperbranched carbohydrate polymers were formed by the cationic polymerization of 1,6-anhydro-beta-D-hexopyranose, 1,4-anhydrotetritol, 2,3-anhydrotetritol, and 1,2:5,6-dianhydro-D-mannitol. These polymerizations proceeded without gelation to produce water-soluble hyperbranched carbohydrate polymers with controlled molecular weights and narrow polydispersities. The values for the degree of branching of the polymers were in the range of 0.28-0.50. The polymerization method, which proceeds through a ring-opening reaction by a proton-transfer reaction mechanism, is a facile method leading to a spherical carbohydrate polymer with a high degree of branching.
本文描述了通过脱水糖和二脱水糖的开环多支化聚合反应制备新型超支化碳水化合物聚合物的过程。超支化碳水化合物聚合物是由1,6-脱水-β-D-吡喃己糖、1,4-脱水四糖醇、2,3-脱水四糖醇和1,2:5,6-二脱水-D-甘露醇的阳离子聚合反应形成的。这些聚合反应不会发生凝胶化，从而生成具有可控分子量和窄多分散性的水溶性超支化碳水化合物聚合物。聚合物的支化度值在0.28 - 0.50范围内。该聚合方法通过质子转移反应机理的开环反应进行，是一种简便的方法，可生成具有高度支化的球形碳水化合物聚合物。
