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拉丁美洲和加勒比地区预防1型人类免疫缺陷病毒母婴传播的错失机会:NISDI围产期研究

Missed opportunities for prevention of mother-to-child transmission of human immunodeficiency virus type 1 in Latin America and the Caribbean: the NISDI perinatal study.

作者信息

D'Ippolito Marcos, Read Jennifer S, Korelitz James, João Esau Custódio, Mussi-Pinhata Marisa, Rocha Neiva

机构信息

Hospital dos Servidores do Estado, Rio de Janeiro, Brazil.

出版信息

Pediatr Infect Dis J. 2007 Jul;26(7):649-53. doi: 10.1097/INF.0b013e3180618bd6.

Abstract

Cases of mother-to-child transmission (MTCT) of human immunodeficiency virus type 1 (HIV-1) in a prospective cohort study in Latin America and the Caribbean were analyzed. Eight of 820 eligible infants became infected [transmission rate, 0.98% (95% CI = 0.45-1.96%)]. Five cases (62%) represented missed opportunities for prevention of MTCT of HIV-1, suggesting the need for ongoing training and education of clinicians regarding prevention of MTCT of HIV-1.

摘要

对拉丁美洲和加勒比地区一项前瞻性队列研究中1型人类免疫缺陷病毒(HIV-1)母婴传播(MTCT)病例进行了分析。820名符合条件的婴儿中有8名感染[传播率为0.98%(95%CI = 0.45 - 1.96%)]。5例(62%)代表了预防HIV-1母婴传播的错失机会,这表明需要持续对临床医生进行关于预防HIV-1母婴传播的培训和教育。

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