痛风患者的红细胞腺苷激酶活性

Erythrocyte adenosine kinase activity in gout.

作者信息

Nishizawa T, Nishida Y, Akaoka I

出版信息

Clin Chim Acta. 1976 Feb 16;67(1):15-20. doi: 10.1016/0009-8981(76)90211-4.

DOI:10.1016/0009-8981(76)90211-4

Abstract

Erythrocyte adenosine kinase (AK) (EC 2.7.1.20) and guanosine monophosphate (GMP) reductase (EC 1.6.6.8) were measured in healthy male controls and primary gout subjects. Adenosine kinase activity in 19 controls and 26 gouty subjects was 0.717 +/- 0.176 and 0.615 +/- 0.128 nmol/mg protein/h, respectively. The difference was statistically significant (p less than 0.05). GMP reductase activity in 39 controls and 46 gouty subjects was 30.90 +/- 6.28 and 33.43 +/- 7.97 mumol/mg protein/h, respectively, without statistically significant difference.

摘要

在健康男性对照组和原发性痛风患者中检测了红细胞腺苷激酶（AK）（EC 2.7.1.20）和鸟苷单磷酸（GMP）还原酶（EC 1.6.6.8）。19名对照组和26名痛风患者的腺苷激酶活性分别为0.717±0.176和0.615±0.128 nmol/mg蛋白/小时。差异具有统计学意义（p<0.05）。39名对照组和46名痛风患者的GMP还原酶活性分别为30.90±6.28和33.43±7.97 μmol/mg蛋白/小时，无统计学显著差异。

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