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无危险因素的准分子原位角膜磨镶术(LASIK)术后延迟性角膜扩张:300微米的基质床足够吗?

Delayed ectasia following LASIK with no risk factors: is a 300-microm stromal bed enough?

作者信息

Tuli Sonal S, Iyer Sandhya

机构信息

Department of Ophthalmology, University of Florida, Gainesville, Fla, USA.

出版信息

J Refract Surg. 2007 Jun;23(6):620-2. doi: 10.3928/1081-597X-20070601-14.

Abstract

PURPOSE

To report a case of ectasia occurring > 4 years following LASIK with no risk factors and a residual stromal bed > 300 microm.

METHODS

A 33-year-old woman presented 4 years after LASIK with mild blurring in the left eye. Uncorrected visual acuity (UCVA) had been 20/20 in both eyes previously.

RESULTS

Uncorrected visual acuity was 20/20 and 20/40 in the right and left eyes, respectively. Best spectacle-corrected visual acuity (BSCVA) was 20/20 with -0.75 +2.25 x 70 degrees refraction in the left eye, which matched topography. Preoperative corneal thickness was 595 microm, and topography showed no risk factors preoperatively or immediately postoperatively. Calculated residual stromal bed was 342 microm and measured 400 microm with ultrasound microscopy. One year postoperatively, UCVA decreased to 20/400, and BSCVA decreased to 20/60 with refraction of -4.50 +5.00 x 90 degrees. The patient was intolerant of contact lens wear and is considering collagen cross-linking, Intacs, or corneal transplantation.

CONCLUSIONS

Ectasia can occur more than 4 years after LASIK. Its etiology is unknown and management is challenging.

摘要

目的

报告1例在准分子原位角膜磨镶术(LASIK)后4年以上出现扩张且无危险因素、残余基质床>300微米的病例。

方法

一名33岁女性在LASIK术后4年出现左眼轻度视物模糊。此前双眼未矫正视力(UCVA)均为20/20。

结果

右眼和左眼的UCVA分别为20/20和20/40。最佳矫正视力(BSCVA)为20/20,左眼有-0.75 +2.25×70度的屈光不正,与地形图相符。术前角膜厚度为595微米,地形图显示术前及术后即刻均无危险因素。计算得出的残余基质床为342微米,超声显微镜测量为400微米。术后1年,UCVA降至20/400,BSCVA降至20/60,屈光不正为-4.50 +5.00×90度。该患者无法耐受佩戴隐形眼镜,正在考虑胶原交联、植入角膜环或角膜移植。

结论

LASIK术后4年以上可能发生角膜扩张。其病因不明,治疗具有挑战性。

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