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在准分子激光原位角膜磨镶术后角膜扩张的角膜中植入角膜环片段。

Intracorneal ring segment implantation in corneas with post-laser in situ keratomileusis keratectasia.

作者信息

Piñero David P, Alio Jorge L, Uceda-Montanes Antonio, El Kady Bassam, Pascual Inmaculada

机构信息

Vissum/Instituto Oftalmológico de Alicante, Spain.

出版信息

Ophthalmology. 2009 Sep;116(9):1665-74. doi: 10.1016/j.ophtha.2009.05.030. Epub 2009 Jul 29.

Abstract

PURPOSE

To evaluate the refractive and aberrometric changes in corneas with post-LASIK keratectasia implanted with intracorneal ring segments (ICRS) during a 2-year follow-up.

DESIGN

Retrospective, consecutive case series.

PARTICIPANTS

Thirty-four eyes of 25 patients (age range, 20-59 years) with post-LASIK ectasia were included. Ectasia was diagnosed by slit-lamp appearance of corneal thinning, unstable topographic steepening, progressive corneal thinning on ultrasonic pachymetry, decreased visual acuity, and unstable refraction.

METHODS

Intracorneal ring segment implantation was performed in all cases by 2 surgeons from 2 different ophthalmologic centers with the aim of correcting the spherocylindrical error and improving the visual quality. Corneal tunnels were created by means of mechanical dissection in 20 eyes and femtosecond laser technology in 14 eyes. Intacs (Addition Technology, Inc, Fremont, CA) were inserted in 24 eyes, and KeraRings (Mediphacos, Belo Horizonte, Brazil) in 10 eyes. In all cases a follow-up of 12 months was completed, with a total of 15 eyes examined 24 months after surgery.

MAIN OUTCOME MEASURES

Uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), refraction, keratometry, and corneal aberrations.

RESULTS

Uncorrected visual acuity did not improve after surgery (P = 0.17). Best spectacle-corrected visual acuity increased significantly at 6 months (P = 0.02). Some 38.89% of eyes gained 2 or more lines of BSCVA at 6 months, and this percentage increased to 60% at 24 months. There was a nonsignificant reduction of sphere at 6 months (P = 0.28). Manifest cylinder was reduced significantly during the postoperative follow-up (P = 0.05, preoperative to 6 months; P = 0.04, 6-12 months). The cornea was on average flatter at 6 months (P<0.01), with a posterior nonsignificant regression of the achieved flattening (P = 0.73). In regard to corneal aberrations, a statistically significant reduction was found in coma-like root mean square (RMS) (P = 0.03) after surgery. Segment ring explantation was performed in 6 eyes, and ring reposition was performed in 2 eyes. The apical curvature gradient was significantly higher in the group of explanted eyes (P = 0.03).

CONCLUSIONS

Intracorneal ring segment implantation is a useful option for the treatment of coma-like aberrations and astigmatism in post-LASIK corneal ectasia.

FINANCIAL DISCLOSURE(S): The author(s) have no proprietary or commercial interest in any materials discussed in this article.

摘要

目的

评估准分子激光原位角膜磨镶术(LASIK)后角膜扩张患者植入角膜内环片(ICRS)后2年随访期间的屈光和像差变化。

设计

回顾性连续病例系列。

研究对象

纳入25例(年龄范围20 - 59岁)LASIK术后角膜扩张患者的34只眼。通过裂隙灯检查发现角膜变薄、地形图不稳定陡峭、超声角膜测厚显示角膜逐渐变薄、视力下降以及屈光不稳定来诊断角膜扩张。

方法

所有病例均由来自2个不同眼科中心的2名外科医生进行角膜内环片植入,目的是矫正球柱镜误差并改善视觉质量。20只眼通过机械剖切创建角膜隧道,14只眼采用飞秒激光技术。24只眼植入Intacs(Addition Technology公司,弗里蒙特,加利福尼亚州),10只眼植入KeraRings(Mediphacos公司,贝洛奥里藏特,巴西)。所有病例均完成了12个月的随访,共有15只眼在术后24个月接受检查。

主要观察指标

裸眼视力(UCVA)、最佳矫正视力(BSCVA)、屈光、角膜曲率测量以及角膜像差。

结果

术后裸眼视力未改善(P = 0.17)。最佳矫正视力在6个月时显著提高(P = 0.02)。约38.89%的眼在6个月时最佳矫正视力提高2行或更多,这一比例在24个月时增至60%。6个月时球镜度数有非显著降低(P = 0.28)。显柱镜度数在术后随访期间显著降低(术前至6个月,P = 0.05;6 - 12个月,P = 0.04)。角膜在6个月时平均变平(P<0.01),所达到的变平程度在后期有非显著的后移(P = 0.73)。关于角膜像差,术后发现类彗差均方根(RMS)有统计学显著降低(P = 0.03)。6只眼进行了节段环取出,2只眼进行了环复位。取出环的眼组的顶点曲率梯度显著更高(P = 0.03)。

结论

角膜内环片植入是治疗LASIK术后角膜扩张中类彗差和散光的一种有效选择。

财务披露

作者对本文讨论的任何材料均无专利或商业利益。

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