Landovitz Raphael J
David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Top HIV Med. 2007 Jun-Jul;15(3):99-103.
Despite major advances in HIV treatment and progress in distribution of antiretroviral therapy in the developing world, staggering rates of new HIV infections persist. Innovative approaches to prevention of transmission are needed. Recent data have confirmed previous observational studies that demonstrated a substantial reduction in acquisition risk with male circumcision and microbicide technology experienced a setback with the early termination of a large-scale vaginal microbicide trial of cellulose sulfate. Limited data from one trial of pre-exposure prophylaxis was not able to validate nor refute efficacy. This article summarizes a presentation on biomedical prevention of HIV infection made by Raphael J. Landovitz, MD, at an International AIDS Society-USA Continuing Medical Education course in Los Angeles in March 2007.
尽管在艾滋病毒治疗方面取得了重大进展，并且在发展中世界抗逆转录病毒疗法的分发方面也取得了进展，但新的艾滋病毒感染率仍然惊人。需要创新的传播预防方法。最近的数据证实了先前的观察性研究，该研究表明男性包皮环切术可大幅降低感染风险，而杀菌剂技术因一项大规模硫酸纤维素阴道杀菌剂试验提前终止而受挫。一项暴露前预防试验的有限数据无法证实或反驳其疗效。本文总结了医学博士拉斐尔·J·兰多维茨于2007年3月在洛杉矶举行的美国国际艾滋病协会继续医学教育课程上所作的关于艾滋病毒感染生物医学预防的演讲。
