Byrnes Matthew C, Coopersmith Craig M
Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.
Curr Opin Crit Care. 2007 Aug;13(4):411-5. doi: 10.1097/MCC.0b013e3281f8d279.
Catheter-related blood stream infections are a morbid complication of central venous catheters. This review will highlight a comprehensive approach demonstrated to prevent catheter-related blood stream infections.
Elements of prevention important to inserting a central venous catheter include proper hand hygiene, use of full barrier precautions, appropriate skin preparation with 2% chlorhexidine, and using the subclavian vein as the preferred anatomic site. Rigorous attention needs to be given to dressing care, and there should be daily assessment of the need for central venous catheters, with prompt removal as soon as is practicable. Healthcare workers should be educated routinely on methods to prevent catheter-related blood stream infections. If rates remain higher than benchmark levels despite proper bedside practice, antiseptic or antibiotic-impregnated catheters can also prevent infections effectively. A recent program utilizing these practices in 103 ICUs in Michigan resulted in a 66% decrease in infection rates.
There is increasing recognition that a comprehensive strategy to prevent catheter-related blood stream infections can prevent most infections, if not all. This suggests that thousands of infections can potentially be averted if the simple practices outlined herein are followed.
导管相关血流感染是中心静脉导管的一种严重并发症。本综述将重点介绍一种已被证明可预防导管相关血流感染的综合方法。
插入中心静脉导管时,预防的重要因素包括正确的手部卫生、使用全面屏障预防措施、用2%氯己定进行适当的皮肤准备,以及将锁骨下静脉作为首选解剖部位。需要严格注意敷料护理,并且应每日评估中心静脉导管的必要性,一旦可行应尽快拔除。医护人员应定期接受预防导管相关血流感染方法的培训。如果尽管床边操作正确但感染率仍高于基准水平,抗菌或抗生素浸渍导管也可有效预防感染。密歇根州103个重症监护病房最近实施的一项采用这些做法的项目使感染率降低了66%。
越来越多的人认识到,预防导管相关血流感染的综合策略即使不能预防所有感染,也能预防大多数感染。这表明,如果遵循本文所述的简单做法,数千例感染有可能得以避免。