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视网膜微血管结构的临床评估及治疗意义。

The clinical assessment of retinal microvascular structure and therapeutic implications.

作者信息

Hughes Alun D

机构信息

Clinical Pharmacology, International Centre for Circulatory Health, NHLI Division, Faculty of Medicine, Imperial College London, St. Mary's Campus, London W2 1NY, UK.

出版信息

Curr Treat Options Cardiovasc Med. 2007 Jun;9(3):236-41. doi: 10.1007/s11936-007-0018-1.

DOI:10.1007/s11936-007-0018-1
PMID:17601388
Abstract

Examination of the retinal microvasculature is widely used to assess diabetic eye disease and as an indicator of target organ damage in hypertension. The diagnostic value of grading of hypertensive retinopathy is dubious; however, many recent studies have demonstrated that hypertensive retinopathy is associated with a range of risk factors for cardiovascular disease and may predict cardiovascular events independently of blood pressure. Developments in digital imaging and computer-assisted analysis have facilitated the quantitative assessment of microvascular changes in cardiovascular disease. These approaches may be useful for assessing cardiovascular risk and targeting therapeutic intervention.

摘要

视网膜微血管检查被广泛用于评估糖尿病眼病,并作为高血压靶器官损害的指标。高血压视网膜病变分级的诊断价值存在疑问;然而,最近许多研究表明,高血压视网膜病变与一系列心血管疾病危险因素相关,并且可能独立于血压预测心血管事件。数字成像和计算机辅助分析的发展促进了心血管疾病微血管变化的定量评估。这些方法可能有助于评估心血管风险并确定治疗干预的目标。

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本文引用的文献

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THE PHYSIOLOGICAL PRINCIPLE OF MINIMUM WORK APPLIED TO THE ANGLE OF BRANCHING OF ARTERIES.应用于动脉分支角度的最小功生理原理
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Value of routine funduscopy in patients with hypertension: systematic review.高血压患者常规眼底检查的价值:系统评价
BMJ. 2005 Jul 9;331(7508):73. doi: 10.1136/bmj.331.7508.73.
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Prevalence and correlates of advanced retinopathy in a large selected hypertensive population. The Evaluation of Target Organ Damage in Hypertension (ETODH) study.大型特定高血压人群中晚期视网膜病变的患病率及其相关因素。高血压靶器官损害评估(ETODH)研究。
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Retinal vascular image analysis as a potential screening tool for cerebrovascular disease: a rationale based on homology between cerebral and retinal microvasculatures.视网膜血管图像分析作为一种潜在的脑血管疾病筛查工具:基于脑与视网膜微血管系统同源性的理论依据。
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