Romanova G A, Silachev D N, Shakova F M, Kvashennikova Yu N, Viktorov I V, Shram S I, Myasoedov N F
Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia.
Bull Exp Biol Med. 2006 Dec;142(6):663-6. doi: 10.1007/s10517-006-0445-0.
Semax had a pronounced neuroprotective and antiamnesic effect during focal photoinduced ischemia of the prefrontal cortex. Intranasal administration of Semax for 6 days decreased the volume of cortical infarction and improved retention and performance of conditioned passive avoidance response.
在局灶性光诱导的前额叶皮质缺血期间,Semax具有显著的神经保护和抗遗忘作用。经鼻给予Semax 6天可减少皮质梗死体积,并改善条件性被动回避反应的保持和表现。