Lermite Emilie, Aubé Christophe, Pessaux Patrick, Arnaud Jean-Pierre
Service de chirurgie viscérale, CHU Angers.
Presse Med. 2007 Jul-Aug;36(7-8):1127-34. doi: 10.1016/j.lpm.2006.12.008. Epub 2007 Jan 17.
The basic principle of radiofrequency ablation is that the deposit of electromagnetic energy in a tumor causes heat ("cooks the tumor") and thereby destroys it. In the liver, this ablation may be performed percutaneously (by needles) or surgically (laparotomy, laparoscopy). Guidance by an imaging technique is necessary: ultrasound, CT or magnetic resonance imaging. The principal hepatic indications are hepatocellular carcinoma and hepatic metastases smaller than <5 cm. There is no associated mortality and only slight morbidity, due principally to hemorrhage, infection or stenosis of the bile ducts. Results show a 5-year survival rate of 40% for hepatocellular carcinoma and 22% for metastases.
射频消融的基本原理是肿瘤内电磁能量的沉积产生热量(“烧灼肿瘤”),从而将其摧毁。在肝脏,这种消融可经皮(通过针)或手术(剖腹术、腹腔镜检查)进行。需要借助成像技术进行引导:超声、CT或磁共振成像。肝脏的主要适应证是直径小于5厘米的肝细胞癌和肝转移瘤。该方法无相关死亡率,发病率也很低,主要是由于出血、感染或胆管狭窄。结果显示,肝细胞癌的5年生存率为40%,转移瘤为22%。