Miller Kai J, denNijs Marcel, Shenoy Pradeep, Miller John W, Rao Rajesh P N, Ojemann Jeffrey G
University of Washington, Department of Physics, Box 351560, Seattle, WA 98195-1560, USA.
Neuroimage. 2007 Aug 15;37(2):504-7. doi: 10.1016/j.neuroimage.2007.05.029. Epub 2007 May 25.
We demonstrate the feasibility of real-time cortical mapping from arrays of subdural electrodes using the electrocorticographic signal power in the higher spectral frequencies (76-200 Hz, or "chi-index"). Hand area was mapped offline in eight individuals using brief baseline and hand-movement measurements. In one patient, hand sensorimotor cortex was identified online during a handshake. We propose that this high-frequency component of the electrocorticogram provides a generic, reliable, clinically useful correlate of local cortical function.
我们通过使用较高频谱频率（76 - 200 Hz，即“chi指数”）的皮层电图信号功率，证明了从硬膜下电极阵列进行实时皮层映射的可行性。利用简短的基线和手部运动测量，对8名个体的手部区域进行了离线映射。在一名患者中，在握手过程中在线识别出了手部感觉运动皮层。我们认为，皮层电图的这种高频成分提供了一种通用、可靠且临床上有用的局部皮层功能关联指标。
