Nakku Juliet E M, Nakasi Grace, Mirembe Florence
Department of Psychiatry, Faculty of Medicine, Makerere University.
Afr Health Sci. 2006 Dec;6(4):207-14. doi: 10.5555/afhs.2006.6.4.207.
Major depression is a common and disabling complication of the postpartum period in women. It is thought to occur three times more commonly in the developing than in developed countries.
The objectives of this study were to determine the prevalence of and factors associated with major depression among women attending a peri-urban primary health care unit in Kampala, Uganda, at six weeks postpartum.
Five hundred and fourty four women attending a peri-urban health centre were investigated in a cross-sectional study. These women were screened using the twenty five-item Self Reporting Questionnaire (SRQ-25), while major depression was confirmed using the Mini International Neuro-psychiatric Interview (MINI). Associations were sought between major depression and the respondents' demographics and various psychological, social and obstetric factors.
The point prevalence of major depression at six weeks postpartum was 6.1%. Psychiatric disorder was significantly associated with young age, being single, negative life events, unplanned pregnancy, unwanted sex of baby and current physical illness in both mother and newborn.
There is indication for routine screening of at risk women in the peri-natal period to avoid, recognize and manage postpartum psychiatric morbidity and its consequence on mothers and their developing children.
重度抑郁症是女性产后常见且致残的并发症。据认为,其在发展中国家的发生率是发达国家的三倍。
本研究的目的是确定乌干达坎帕拉一个城郊初级卫生保健单位产后六周妇女中重度抑郁症的患病率及其相关因素。
在一项横断面研究中,对544名到城郊卫生中心就诊的妇女进行了调查。这些妇女使用25项自评问卷(SRQ - 25)进行筛查,同时使用迷你国际神经精神访谈(MINI)确诊重度抑郁症。研究了重度抑郁症与受访者的人口统计学特征以及各种心理、社会和产科因素之间的关联。
产后六周重度抑郁症的时点患病率为6.1%。精神障碍与年轻、单身、负面生活事件、意外怀孕、婴儿性别不理想以及母亲和新生儿目前的身体疾病显著相关。
有迹象表明,围产期应对高危妇女进行常规筛查,以避免、识别和管理产后精神疾病及其对母亲和发育中儿童的影响。