Moodley Nivan, Crouch Neil R, Mulholland Dulcie A
School of Chemistry, University of KwaZulu-Natal, Howard College Campus, Durban 4041, South Africa.
Phytochemistry. 2007 Oct;68(19):2415-9. doi: 10.1016/j.phytochem.2007.05.023. Epub 2007 Jul 2.
The bufadienolides, rubellin and riparianin were isolated from the bulbs of Drimia macrocentra and Urginea riparia (Hyacinthaceae) respectively. Rubellin and riparianin contain a carbohydrate moiety doubly linked to the bufadienolide aglycone at the C-2 and C-3 positions. Riparianin showed moderate activity when tested against MCF7 (breast), TK10 (renal) and UACC62 (melanoma) cell lines.
蟾蜍二烯羟酸内酯、红铃蟾蜍二烯羟酸内酯和河岸蟾蜍二烯羟酸内酯分别从大中心绵枣儿和河岸绵枣儿(风信子科)的鳞茎中分离得到。红铃蟾蜍二烯羟酸内酯和河岸蟾蜍二烯羟酸内酯在C-2和C-3位含有一个与蟾蜍二烯羟酸内酯苷元双连接的碳水化合物部分。河岸蟾蜍二烯羟酸内酯在针对MCF7(乳腺癌)、TK10(肾癌)和UACC62(黑色素瘤)细胞系进行测试时表现出中等活性。